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What are the requirements for PEP?

Editorial team Published on
To get Post-Exposure Prophylaxis (PEP) for HIV, you must act immediately (within 72 hours of exposure) by going to an emergency room, urgent care clinic, or health clinic to be evaluated by a doctor, who will prescribe it if appropriate, as PEP is an emergency treatment to prevent HIV after potential exposure. You'll need an HIV test and other STD screenings, and must take the medication daily for 28 days, with follow-up care required.
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How do you qualify for PEP?

You May Qualify for PEP if:

You were exposed or had a possible exposure within the past 72 hours. You have frequent exposure to HIV and want to transition to PrEP.
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What are the guidelines for taking PEP?

Post-exposure prophylaxis (PEP) refers to a short course (28 days) of HIV medicines that are taken after a possible exposure to prevent HIV infection. PEP must be started within 72 hours after a possible exposure to HIV. The sooner PEP is started after a possible HIV exposure, the better. Every hour counts.
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Who qualifies for PEP treatment?

If you are 16 and older and live in England, you are eligible to access PrEP if: You are a man who has anal sex with other men without condoms. You are a trans man or trans woman and you have anal sex or front sex without condoms. Your regular partner is living with HIV which is not fully controlled on treatment.
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Who is eligible for PEP?

PEP can be taken when there has been a risk that you have come into contact with HIV. This can be after unprotected sex or a condom break with someone who is at high risk of having HIV. It can also be taken if you have been sharing drug injecting equipment.
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How much does PEP usually cost?

The cost of PEP ranges from $600 to over $1,000. Medicaid and many other health insurance plans cover PEP in full or in part. If you don't have insurance, talk to your medical provider about available drug assistance programs.
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Can you be denied PEP?

A health care provider must verify that you are currently HIV-negative before prescribing PEP. If your test is positive (indicating an infection pre-dating your exposure), the provider will discuss making a treatment plan with you. If you refuse HIV testing, you may be unable to receive PEP.
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Is PEP as good as PrEP?

PrEP can be more effective than PEP:

PEP isn't 100% effective, and it won't prevent future HIV infections like PrEP can. So it's important to keep protecting yourself and others from HIV while you're on PEP by using condoms or taking PrEP.
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Can straight men take PrEP?

PrEP is for anyone – straight, gay, or bisexual. PrEP is for male, female, transgender, or gender non-conforming individuals. PrEP is for people who are HIV negative (not living with HIV). When a person takes PrEP as directed, it is 99% effective at preventing HIV.
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How long is too late for PEP?

PEP is a treatment that can stop an HIV infection after the virus has entered a person's body. It must be taken as soon as possible after exposure but within 72 hours.
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How long does a PEP usually last?

PEP is usually taken for four weeks and should be started as soon as possible after exposure to HIV.
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How long does PEP stay in your system?

PEP is different from PrEP, a prescription medication for people at risk of exposure to prevent HIV before potential exposure. There is no firm research regarding exactly how long PEP drugs remain in the body. Experts suspect it is probably not longer than 24 to 48 hours. A 28-day PEP prescription covers one exposure.
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What to avoid while on PEP?

What should I do after I start PEP? It is important to take your daily PEP medication and use condoms. After you've completed your 28-day course of medication, we will retest you for HIV. Other things to avoid include needle sharing, chestfeeding, donating blood, plasma, organs, tissue, or semen.
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How effective is PEP if taken immediately?

With a combination of three drugs, HIV PEP will almost certainly prevent HIV infection if taken within 48 hours after exposure. However, efficacy will decrease steeply after this time. If taken between 48 and 72 hours after exposure, regardless of the number of drugs, PEP is much less likely to be effective (7, 17–20).
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Can a PEP be rejected?

While the designation is meant to prevent corruption, in reality, many PEPs are blocked, denied services, or even sanctioned without evidence of wrongdoing. If your relative or employer is under OFAC or EU sanctions, your proximity can trigger an investigation.
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What are the three types of PEP?

Bearing in mind the broad scope of what is a PEP, the FATF has further divided PEPs into three primary categories, namely Foreign, Domestic, and International Organization PEPs. Foreign PEPs: These are individuals who hold or have held prominent public positions in a foreign country.
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What is the 2 1 1 rule for PrEP?

PrEP 2-1-1 starts by taking TWO pills between 2 and 24 hours before sex. Taking the pills closer to 24 hours before sex is better but you can use PrEP 2-1-1 up to 2 hours before sex. After sex, you take ONE pill 24 hours after the first pills, and ONE pill again 24 hours after that.
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Who cannot take PrEP?

Who may not be able to take PrEP
  • have ever had an allergic reaction to tenofovir disoproxil, emtricitabine or any other medicine.
  • have severe liver or kidney problems.
  • are pregnant or breastfeeding.
  • have a weakened immune system (immunocompromised)
  • are HIV positive.
  • have hepatitis.
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What is the fail rate of PrEP?

Its effectiveness in preventing HIV has been attested at 86% in trials [4,5] and as high as 95% when adherence is optimal [6]. HIV seroconversion in PrEP users is infrequent and its prevalence has been estimated at around 3% [7], with most PrEP 'failures' attributed to poor adherence.
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Is there a downside to taking PEP?

PEP can cause mild side effects including nausea, upset stomach, fatigue, and headaches. These symptoms often get better or go away completely after the first week of taking PEP. For nausea, take PEP with a snack, before bed, or try ginger candy or peppermint tea.
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Do I need PEP if I'm on PrEP?

People who are already using PrEP typically do not need PEP if they experience a potential HIV exposure while taking their PrEP medication as prescribed.
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Is PrEP really 99% effective?

PrEP (Pre-Exposure Prophylaxis) is highly effective at preventing HIV, reducing risk by about 99% for sexual transmission and at least 74% for injection drug use, when taken as prescribed. Consistency is crucial; missing doses lowers effectiveness, while taking it daily or regularly (e.g., 4+ times/week for oral PrEP) ensures maximum protection, which takes about 20 days to build for vaginal/injection use and 7 days for anal sex. It's for HIV-negative individuals at risk and should be paired with condoms for other STIs.
 
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Why are doctors hesitant to prescribe PEP?

The doctor listened, conducted some research, and eventually wrote the prescription. A common refrain among doctors who don't want to prescribe PrEP is that it doesn't prevent other sexually transmitted diseases or infections, but Mason said comparing HIV with infections like gonorrhea isn't right.
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How much does PEP cost?

Depending on your pharmacy, a full course of of PEP (truvada + tivicay/isentress) costs between $600 and $2,500 without insurance.
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Do tops need to take PrEP?

Generally, it is recommended that tops take PrEP to reduce the risk of HIV transmission, as both partners can carry and pass on the virus - even during insertive sex. Ultimately, the decision to take PrEP is up to the individual and should be done in consultation with a healthcare practitioner.
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