What is the new alternative to EpiPen?

The main new EpiPen alternative is neffy, the first FDA-approved, needle-free epinephrine nasal spray for anaphylaxis, offering a less intimidating option for emergency treatment, especially for children, though doctors often recommend keeping an injectable backup while more real-world data is gathered. While neffy (approved for ages 4+, 33+ lbs) is convenient, it has potential side effects like nasal irritation, and its effectiveness in actual anaphylaxis needs more study, so always discuss with your allergist.

What is replacing the EpiPen?

Now, there's another option when an emergency strikes. In August 2024, the U.S. Food and Drug Administration (FDA) approved the first-ever nasal spray to treat life-threatening allergic reactions. The spray, known as neffy®, also contains epinephrine, the same medication found in EpiPens® (epinephrine auto-injectors).

When will neffy be available?

In March 2025, FDA approved a 1 mg neffy nasal spray for children ages 4 and older weighing between 33 and 66 pounds. This device is expected to be available for prescription in May 2025. A neffy prescription consists of two single-dose nasal spray devices. Each device is a single dose administered into one nostril.

How much is neffy with insurance?

Neffy is available for as low as $25 with commercial insurance and specific health plans or a cash price of $199. This eliminates people having to weigh their options when determining whether or not their allergic reaction is “severe enough” to administer epinephrine.

Does neffy work faster than EpiPen?

Across a range of studies, neffy has demonstrated a pharmacokinetic profile that is within the range of currently approved injection products, as well as pharmacodynamic responses that are as good or better than injection, including a response observed as early as one minute after treatment, which confirms activation ...

Low-cost alternatives to EpiPen available now

How do you buy Neffy?

Getting started is simple - no waiting rooms, no travel, no cost*.

1. Complete a quick medical form.
2. Schedule a FREE* virtual visit with a prescriber. ...
3. Meet with a prescriber. ...
4. neffy can be picked up at the pharmacy of your choice or sent directly to your home†

Can you survive anaphylaxis without an EpiPen?

Severe untreated anaphylaxis can lead to death within half an hour. Get emergency treatment even if symptoms start to improve.

Is Neffy prescription only?

But Neffy is available now for prescription, so if you want to learn more about it, please talk with your allergist to learn more.

How to qualify for Neffy?

neffy is available through many insurance plans

If neffy is not covered by your insurance, it may require a prior authorization ‐ which requires your doctor to submit additional paperwork. Contact your doctor to ensure all paperwork has been submitted.

Can you buy budesonide over the counter?

Budesonide nasal spray (Rhinocort Allergy) is an over-the-counter (OTC) allergy medication for adults and children age 6 years and older. It's a corticosteroid that relieves nasal allergy symptoms, such as runny or stuffy nose, itchy nose, and sneezing.

What should I avoid while using Neffy?

NEFFY Lifestyle Interactions

Notes for Consumers: Limit excessive Caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Epinephrine and avoid medicines containing additional Caffeine whenever possible.

What age is Neffy approved for?

neffy is a nasal spray used for emergency treatment of allergic reactions including anaphylaxis, in adults and children aged 4 years and older who weigh 33 lbs or greater.

Are there alternatives to Neffy?

“Your allergist may recommend keeping injectable epinephrine as a back-up option in addition to Neffy.” Also, be sure to tell your provider if you've ever broken your nose, had nasal surgery or have structural issues like polyps, as these could interfere with medication absorption.

Has anyone used Neffy yet?

Meet Anna: a real neffy patient

This is a game changer for us, and it's extremely meaningful to me that she can get epinephrine without a needle.” My daughter has used neffy a few times, and we're grateful to have something that works quickly and effectively.”

What is the next best thing to an EpiPen?

Patients can purchase the authorized generic for Adrenaclick® at the low cost cash price of $109.99 for a two-pack. This authorized generic is a Food and Drug Administration (FDA)-approved device with the same active ingredient as other epinephrine auto-injector devices.

Is Neffy cheaper than Epi?

neffy is priced at $199 for a two-pack, making it a more affordable option for many patients. This lower cost could make life-saving epinephrine more accessible to a wider range of people, especially those without insurance or those who need to buy multiple devices to keep at home, school, and work.

How quickly does Neffy work?

neffy starts to work in under a minute, providing fast, dependable epinephrine. neffy delivers the same epinephrine found in needle-injectors, and works the same way in your body, including increasing blood pressure and heart rate. The nasal spray can get through stuffy noses.

Will urgent care give you an EpiPen?

Other Ways Urgent Care Can Help

Here's how our team can help: Allergy Assessment: Providers can evaluate your symptoms, determine the severity, and offer treatment if needed. Medications: Antihistamines, corticosteroids, or epinephrine may be administered to manage symptoms.

What are the side effects of Neffy?

Common side effects of neffy include: nasal discomfort, headache, throat irritation, chest and nasal congestion, feeling overly excited, nervous or anxious, nose bleed, nose pain, sneezing, runny nose, dry nose or throat, tingling sensation, including in the nose, feeling tired, dizziness, nausea, and vomiting.

Does Flonase help with post nasal drip?

Sometimes when mucus builds up it can cause a bacterial infection, and you'll need antibiotics to help clear it up. Does Flonase help with postnasal drip? Flonase is an OTC steroid nasal spray that treats sneezing, itchy, or runny nose caused by seasonal allergies. It can help stop a runny nose and postnasal drip.

How do I get the Neffy on us program?

For more information about Get neffy on Us, visit www.getneffy.com or call 1-877-MY-NEFFY (1-877-696-3339). The program is part of ARS Pharma's ongoing commitment to reducing barriers for people who want to experience the ease of carrying a needle-free, lifesaving medicine to treat their allergies.

What is the generic name for Neffy?

Neffy (epinephrine) is a non-selective alpha- and beta-adrenergic receptor agonist that acts on receptors (signaling proteins) throughout the body. In doing so, it keeps your blood pressure from dropping too low, raises your heart rate, and opens your lungs so you can breathe normally.

What is the rule of 2 for anaphylaxis?

Think of a "rule of 2's" for anaphylaxis implying that reactions usually begin within 2 minutes to 2 hours after injection, infusion, ingestion, contact, or inhalation.

Does Zyrtec prevent anaphylaxis?

Antihistamines are recommended for treatment of mild and moderate allergic reactions, including allergic rhinitis (hay fever), but have no role in treating or preventing respiratory and cardiovascular symptoms of anaphylaxis.

What could be mistaken for anaphylaxis?

Acute urticaria and angioedema, which involve localized skin reactions and swelling, can sometimes mimic the systemic nature of anaphylaxis.